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Doberman Pinscher
#1
Doberman Pinscher

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Breed Origins: Germany ( 1800's ) 

Dog Weight: 65 - 90 Pounds 

Dog Height: 24 to 28 inches to the shoulder 


Information, Facts & Origins of the Doberman Pinscher Dog Breed

The Doberman Pinscher originates from Germany and was bred originally as a guard dog. It's origins can be dated back to the 1800's. The Doberman Pinscher is also known by the other name of the Dobermann and was named after Louis Dobermann of Apolda in Thuringen, Germany. Dobermann was a tax collector and dog pound keeper who wanted watchful guard dog to accompany him on his rounds. It is believed that he crossed many breeds including the German Shepherd, Rottweiler, German Pinscher, Terrier, Greyhound and Weimaraner to produce the Doberman Pinscher. This dog is classified as one of the Working Dog Group which we go on to describe in detail in the section at the bottom of this page. The Doberman Pinscher was first Registered by the AKC (American Kennel Club) in 1908. Name Facts and Dog Names: This dog's name is often referred to as the German Pinscher and the Dobermann Pinscher. The word Pinscher is often mis-spelt as Pincher and Pinsher.

Description of the Doberman Pinscher Dog Character and Temperament

Working dogs, like the Doberman, are medium to giant size and are strong, often independent, domineering and difficult to manage. This, together with the immense sizes of many of the breeds, make many of the working dogs unsuitable as a normal family pet or first time dog owners. These dogs require firm control and must be properly trained. Formal obedience training should include a proper socialising program. Training need not be difficult as Working dog breeds are generally quick to learn and intelligent. Some of the working dog breeds are easier to handle such as the Newfoundland dog, the Portuguese Water Dog, the Samoyed and the Saint Bernard.

Description of the Doberman Pinscher Dog and Puppies - Coat and Colours information

The Doberman Pinscher's coat is normally a shade of black, brown, blue and fawn with rust marking on their head, body and legs. The coat is normally short, smooth, thick and close.

Dog Health information - potential health problems of the Doberman Pinschers

All owners of dogs and puppies are concerned about the health care of their pets and just as with humans dog health issues arise from time to time. Resolving dog health problems, including those of the Doberman Pinscher, can prove to be costly and it would be wise to consider the benefits of obtaining dog health insurance. Diseases in dogs may occur because of trauma, infection, immune system abnormalities, genetic factors, or degenerative conditions. Common health problems and questions occur in relation to the Bones, Joints, Muscles, Nerves, Ears, Eyes, Teeth and the Mouth. Other, more serious, issues can relate to the Digestive System, Heart & Respiratory Systems, Immune & Blood Systems, Reproduction and Urinary Systems. Potential health problems of the Doberman Pinscher can include:

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Hip and Elbow Dysplasia (abnormal development of joints referred to as CHD - Canine Hip and Elbow Dysplasia)
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Gastric Torsion
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CVI (cervical vertebral instability) also known as "Wobbler Syndrome" a disease of the spinal column of the neck 

Information on Grooming and Care of the Doberman Pinscher Dog Breed 

The Doberman Pinscher requires weekly care and grooming. All dog breeds require a certain amount of grooming and care is necessary to keep dogs and puppies looking at their best. Grooming consists of not only brushing out the coat and bathing but also giving attention to the eyes, teeth, ears, feet and nails. A regular routine also ensures that any potential health problems are identified as quickly as possible, especially important in puppies and older Doberman Pinscher dogs.

Life Expectancy 

The life expectancy for this particular breed is 12 – 15 years.

Age comparisons between dogs and humans are always a matter of debate - we hope that the following information clarifies the situation. After the first year of life, a dog is equivalent to sixteen human years. After two years, they are equivalent to a 24 year old, at three years a 30 year old, and each year after, add 5 human years to determine a dog's age.

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#2
Human 'Albino' Gene Found in Dogs

By Elizabeth Palermo, Live Science Contributor | May 16, 2014 07:08am ET

[Image: albino-doberman-pinschers_zpsf076280d.jpg]
Albino Doberman pinschers share a similar gene with humans who also have the condition, scientists say.

Dogs and people have more in common than a love of Frisbees and long walks on the beach. A new study finds that certain dogs, just like certain humans, carry a gene mutation that causes albinism — a condition that results in little or no pigment in the eyes, skin and hair. 

The study by researchers at Michigan State University identifies the exact genetic mutation that leads to albinism in Doberman pinschers, a discovery that has eluded veterinarians and dog breeders until now. Interestingly, the same mutated gene that causes albinism in this dog breed is also associated with a form of albinism in humans.

"What we found was a gene mutation that results in a missing protein necessary for cells to be pigmented," study co-author Paige Winkler, a doctoral student in the College of Veterinary Medicine at Michigan State University in East Lansing, Michigan, said in a statement. 

Winkler said the gene mutation found in Doberman pinschers is responsible for a condition known as oculocutaneous albinism, which also affects humans. The condition expresses certain characteristics in both humans and dogs.

"With an albino Doberman, you see a white or lighter-colored coat, pink noses and lips, along with pale irises in the eyes," Winkler said. "These traits are very similar to the characteristics humans display with this particular condition, causing light-pigmented skin and hair, along with eye discoloration and vision disturbances."

Just as people with this type of albinism experience skin sensitivity to sunlight, which can result in an increased vulnerability to skin tumors, canines with the mutated gene were also found to be at higher risk for developing skin tumors, the researchers said.

"We knew that albino Dobermans typically developed these types of tumors, much like [albino] humans, but we wondered what the actual increase in prevalence was between a 'white' dog and a regular-colored Doberman," said Joshua Bartoe, an assistant professor in the Department of Small Animal Clinical Sciences at Michigan State University, who co-led the study. "What we found was a significant increase in risk for development of melanoma-like tumors in the albino dogs."

These findings were based on a study of 40 Dobermans pinschers — 20 albino dogs and 20 "regular-colored" dogs. The researchers found that more than half of the albino dogs had at least one tumor, while only one of the regular-colored dogs had a tumor.

Bartoe and Winkler said their study could serve as a valuable resource for Doberman breeders around the world, particularly because the American Kennel Club, a registry of purebred dog pedigrees in the United States, doesn't allow the registration of albino dogs.

"Because Dobermans can carry the defective gene, but show no signs of the [condition], this has posed serious problems among breeders," Bartoe said. "But now that we've identified the mutation, we can look at the genetic makeup of these dogs and determine if they might be carriers."

The results of the new study were published March 19 in the journal PLOS ONE.

http://www.livescience.com/45646-humans-dogs-albino-gene.html




A Partial Gene Deletion of SLC45A2 Causes Oculocutaneous Albinism in Doberman Pinscher Dogs

Paige A. Winkler, Kara R. Gornik, David T. Ramsey, Richard R. Dubielzig, Patrick J. Venta, Simon M. Petersen-Jones, Joshua T. Bartoe 
Published: March 19, 2014DOI: 10.1371/journal.pone.0092127

Abstract
The first white Doberman pinscher (WDP) dog was registered by the American Kennel Club in 1976. The novelty of the white coat color resulted in extensive line breeding of this dog and her offspring. The WDP phenotype closely resembles human oculocutaneous albinism (OCA) and clinicians noticed a seemingly high prevalence of pigmented masses on these dogs. This study had three specific aims: (1) produce a detailed description of the ocular phenotype of WDPs, (2) objectively determine if an increased prevalence of ocular and cutaneous melanocytic tumors was present in WDPs, and (3) determine if a genetic mutation in any of the genes known to cause human OCA is causal for the WDP phenotype. WDPs have a consistent ocular phenotype of photophobia, hypopigmented adnexal structures, blue irides with a tan periphery and hypopigmented retinal pigment epithelium and choroid. WDPs have a higher prevalence of cutaneous melanocytic neoplasms compared with control standard color Doberman pinschers (SDPs); cutaneous tumors were noted in 12/20 WDP (<5 years of age: 4/12; >5 years of age: 8/8) and 1/20 SDPs (p<0.00001). Using exclusion analysis, four OCA causative genes were investigated for their association with WDP phenotype; TYR, OCA2, TYRP1 and SLC45A2. SLC45A2 was found to be linked to the phenotype and gene sequencing revealed a 4,081 base pair deletion resulting in loss of the terminus of exon seven of SLC45A2 (chr4:77,062,968–77,067,051). This mutation is highly likely to be the cause of the WDP phenotype and is supported by a lack of detectable SLC45A2 transcript levels by reverse transcriptase PCR. The WDP provides a valuable model for studying OCA4 visual disturbances and melanocytic neoplasms in a large animal model.

http://www.plosone.org/article/info:doi/10.1371/journal.pone.0092127 
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